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Ezekiel Price
Ezekiel Price

Alpha Hydrox Where To Buy



α-Hydroxy acids, or alpha hydroxy acids (AHAs), are a class of chemical compounds that consist of a carboxylic acid with a hydroxyl group substituent on the adjacent (alpha) carbon. Prominent examples are glycolic acid, lactic acid, mandelic acid and citric acid.




alpha hydrox where to buy



Although these compounds are related to the ordinary carboxylic acids and are therefore weak acids, their chemical structure allows for the formation of an internal hydrogen bond between the hydrogen at the hydroxyl group and one of the oxygen atoms of the carboxylic group. The net effect is an increase in acidity. For example, the pKa of lactic acid is 3.86, while that of the unsubstituted propionic acid is 4.87; a full pKa unit difference means that lactic acid is ten times stronger than propionic acid.[1][2]


Who Should Use It: Given their wide range of effects, most people can benefit from using AHAs, says Nazarian, so long as you find the right alpha-hydroxy acid and concentration of it for your skin type.


Don't Use With: Avoid using retinoids at the same time of day as AHAs, and be cautious when using both BHAs (beta hydroxy acids, such as salicylic acid) and AHAs in order to minimize irritation.


How often you use alpha-hydroxy acid depends on the particular acid, product, and skin. Follow product directions, but always start slow, using any AHA only once or twice per week and gradually increasing frequency as your skin can tolerate it.


Alpha hydroxy acids are a group of natural acids found in foods. Alpha hydroxy acids include citric acid (found in citrus fruits), glycolic acid (found in sugar cane), lactic acid (found in sour milk), malic acid (found in apples), tartaric acid (found in grapes), and others.


Various alpha hydroxy acids are applied to the skin (used topically) for moisturizing and removing dead skin cells, for treating acne and improving the appearance of acne scars, for improving the appearance of photo-aged skin, and firming and smoothing skin.


  • Treating sun damage when applied to the skin in a cream or lotion, but alpha hydroxy skin peels do not seem to work for this use.

  • Treating dry skin when applied to the skin in a cream or lotion.



  • Treating an inherited skin disorder that causes dry, scaly skin (ichthyosis).

  • Other conditions.

More evidence is needed to rate alpha hydroxy acids for these uses.


Alpha hydroxy acids at a concentration of 10% or less as a lotion or cream are LIKELY SAFE for most people when applied to the skin appropriately and as directed. In some people, alpha hydroxy acids can make the skin extra sensitive to sunlight. Be sure to use a sunscreen while using alpha hydroxy acid products.


  • APPLIED TO THE SKIN:For treating skin wrinkled and aged by sunlight: Alpha hydroxy acid products containing lactic acid, tartaric acid, gluconolactone, or glycolic acid (GA) in 8% concentration are used. The alpha hydroxy acid gluconolactone has also been used in a 14% solution. These products are usually applied to the skin twice daily.

  • For improving the appearance of acne scars: glycolic acid (GA) facial peels are used. Peels of increasing strength of 20%, 35%, 50%, and 70% are applied every two weeks. Peels are applied first for 2 minutes and then for a longer time (up to 4-5 minutes) before applying the next stronger solution. Completing the series at least 6 times is usually needed before skin looks better. People who do not like facial peels often use 15% GA lotion daily long-term instead.

  • For lightening brown patches due to a condition called melasma: a 10% lotion of the glycolic acid (GA) is applied with a sunscreen to facial skin nightly for 2 weeks. Then a peeling program is done monthly for 3 months in a row. The peeling program features a 50% GA peel applied three times to the face and left on for a period of 2-5 minutes each time (first peel 2 minutes, second peel 4 minutes, and third peel 5 minutes).



Ditre CM, Griffin TD, Murphy GF, et al. Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study [see comments]. J Am Acad Dermatol 1996;34:187-95. View abstract.


Kempers S, Katz HI, Wildnauer R, Green B. An evaluation of the effect of an alpha hydroxy acid-blend skin cream in the cosmetic improvement of symptoms of moderate to severe xerosis, epidermolytic hyperkeratosis, and ichthyosis. Cutis 1998;61:347-50. View abstract.


When it comes to choosing between alpha hydroxy acids vs retinol, which is best for your skin? Reducing the effects of aging on your skin requires a combination of ingredients including broad spectrum sunscreens, exfoliants (like alpha hydroxy acids or AHAs), antioxidants, emollients, and cell communicating ingredients like retinol. Derived from Vitamin A, ingredients like retinol and prescription only retinoic acid, are widely recommended by skin care professionals for their ability to help reverse sun damage, reduce the appearance of wrinkles, boost collagen production and increase skin cell turnover. While many individuals cannot tolerate tretinoin because it is highly irritating to skin, retinol and retinaldehyde are over the counter alternatives that are effective and better tolerated.


Hi Annika,Your skin is tingling upon application of your alpha hydroxy acids because the product is penetrating the epidermis, or top layer of your skin. This is a normal side-effect and should diminish with continued use. A tingling, burning sensation can also occur when you have sunburn, allergies, a cold or fatigue. If the tingling sensation is bothering you, gently rinse the product off. If you have especially sensitive skin, you may find the aha cream Green Cream Level 3 works well for you without irritating your skin. See our advice on using retinol creams.


Hello Nicole, the best way to use alpha hydroxy acids and retinol is alternately. Both are effective treatments in resurfacing the skin, but together they may cause undue irritation. I should imagine the same to be true of AHAs and Porcelana. I would advise you to use them alternately. If you wish to try layering, proceed with caution: do a patch test first on an inconspicuous area and wait 24 hours for any symptoms to appear. Hope this helps, Sharmani.


For Judy:Both retinoids and alpha hydroxy acids are great as part of your anti-aging skin care routine. We would suggest that they be used on alternating nights in order to minimize any possible irritation. And because both can make you more sun sensitive, daily application of a good, broad spectrum sunscreen like Anthelios is essential.Best, Sharmani


For Ash:Retinoids and vitamin A products should be avoided if you are pregnant, trying to get pregnant or breastfeeding. As for alpha hydroxy acids, they are generally considered safe but it would be best to consult with your doctor.Best, Sharmani


Hi. I am 32 with acne prone skin and use proactiv repairing lotion every night. I want to start incorporating both retinol and aha into my skincare regime but not sure how to do it effectively. I started using Roc Retinol at night, followed by Proactiv a half hour later, but I recently read somewhere that benzoyl peroxide (the active ingredient in proactiv) deactivates retinol. I really want to start regularly using retinol because i am starting to see signs of aging but afraid if I stop proactiv that I will breakout worse. i dont want to use proactiv in the day because its drying and causes sensitivity to sun. Do you have any tips on how I can effectively & correctly use all 3 products: retinol, aha, & proactiv? Thank u so much for your help! : )


I have a question- i use glycolic acid cream 10% every morning under my vitamic c- then I use cerave PM moisturizer- i have oily skin- can i skin mositurizer- or add like a hyaluronic serum. at nite i use vitamic c and then olay regenerist. plus i use eye cream. I clean my face morning and nite with a konjac sponge with Cerave hydrating cleanser. what should i be doing different. I am 41 with oily skin. I hear hyaluronic serums are great too but where do u add them in? do i need a better Retinol at night besides Olay.


For Hyra,Keratosis pilaris can treated with a range of different ingredients to help exfoliate, like alpha hydroxy acids, urea or retinoids, depending on where on the body it is occurring. Read more about your options here in our blog post that deals specifically with this issue.Best, Sharmani


The effect of various organic acids on hydroxyl radical (.OH) generation in the Fenton reaction were examined by the ESR spin trapping technique, where 5,5-dimethyl-1-pyroline-N-nitroxide (DMPO) and alpha-phenyl-tert-butyl nitrone (PBN) were used as the spin trapping reagents. alpha-Hydroxy acids such as lactic acid, glycolic acid and 2-hydroxy isobutyric acid were found to markedly enhance .OH generation in the reaction. In contrast, beta-hydroxy acid, alpha-keto acid, esters of alpha-hydroxy acids, aldehydes and other straight chain organic acids had no such enhancing activity. alpha-Amino acids had also no enhancing effect. The results suggest that the alpha-hydroxy acid moiety is prerequisite for the enhancement of .OH generation in the Fenton reaction. Superoxide dismutase did not inhibit the enhancing effect of alpha-hydroxy acids whereas catalase completely inhibited the .OH generation. Thus, alpha-hydroxy acids directly enhanced the .OH generation via the Fenton reaction but not the Haber-Weiss reaction. Possible role of lactic acid manipulating .OH generation is discussed in relation to the ischemia-reperfusion cell damage.


Alpha-hydroxy acids include glycolic, lactic, tartaric, malic, and citric acids. They have become increasingly popular over the last 20 years. In the U.S. alone, there are over 200 makers of skin care products containing alpha-hydroxy acids.


Creams and lotions with alpha-hydroxy acids may help with fine lines, irregular pigmentation, and age spots. Side effects of alpha-hydroxy acids include mild irritation and sun sensitivity. For that reason, sunscreen should be used every morning. 041b061a72


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